Saint Francis University (SFU) is a private Catholic liberal arts university in Loretto, Pennsylvania. It was founded in 1847 and conducted under the tradition of the Franciscan Friars of the Third Order Regular. The university is situated on 600 acres (243 ha) in the forests and farmland of Loretto.

The university was one of the first Catholic universities in the United States and the first Franciscan college in the nation. Although it originally only admitted males, it became one of the first Catholic Universities to become co-educational.

Saint Francis University enrolls approximately 1704 undergraduate students (of whom 37% are male and 63% female) and 605 graduate students The university offers 25 undergraduate majors and 7 graduate fields of study (including Physical Therapy, in which the University awards a doctorate) to its students. The university maintains an average graduation rate of 70.3%.